As the embryo is contained in a layer of proteins known as zona pellucida, this outer structure protects the embryo cell from damage. In order to successfully implant into the uterine lining an embryo has to hatch out of the zona pellucida and attach to the walls of the uterus. Assisted hatching is a technique to create a small hole at zona pellucida or thin out zona pellucida. This technique can increase implantation. Especially, it is very helpful for the frozen – thaw embryo or embryo with a thinker zona pellucida than normal or the woman with advanced maternal age, etc.
With assisted hatching, an embryologist uses laser assisted-hatching; it is faster, more accurate and safer for the embryos. Typically, this procedure is carried out on the same day as embryo transfer.